A new study has found a direct correlation between the presence of certain bacteria in the intestine of patients and the incidence of lymphoma.
The JCCC at UCLA University followed the life of mice with Ataxia telangiectasia, a disease that is connected to a high rate of B cell lymphoma in humans and mice.
A person's microbiome, the complex of diverse flora in the body and bacterial count contains at least one thousand species, and is often influenced by diet and lifestyle.
A study of the different microbiomes to see if there was a distinct pattern with those mice that developed lymphoma, yielded some very interesting results.
At the end of the study, mice who had a specific microbiome developed the lymphoma much later in life and had less genotoxicity (gene damage) that is the cause of lymphoma.
This indicates that some animals and people have bacteria in their microbiome that are protective against the genotoxicity that causes lymphoma.
There are two types of lymphoma, Hodgkin's lymphoma and non-Hodgkins Lymphoma. The latter is much more deadly than the former. It is not a rare disease either. 1 in every 50 Americans are at risk of developing the disease.
This research could afford the patient new therapies that could be used in tandem with other recently discovered compounds that block the protein BCL6, which is what causes cancers in about 50% of all non-Hodgkin's cases.
Source : MNT/ 7.17.13
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